Insecticidal Bed Nets and Filariasis Transmission in Papua New Guinea
نویسندگان
چکیده
منابع مشابه
Insecticidal bed nets and filariasis transmission in Papua New Guinea.
BACKGROUND Global efforts to eliminate lymphatic filariasis are based on the annual mass administration of antifilarial drugs to reduce the microfilaria reservoir available to the mosquito vector. Insecticide-treated bed nets are being widely used in areas in which filariasis and malaria are coendemic. METHODS We studied five villages in which five annual mass administrations of antifilarial ...
متن کاملMass treatment to eliminate filariasis in Papua New Guinea.
BACKGROUND The global initiative to eradicate bancroftian filariasis currently relies on mass treatment with four to six annual doses of antifilarial drugs. The goal is to reduce the reservoir of microfilariae in the blood to a level that is insufficient to maintain transmission by the mosquito vector. METHODS In nearly 2500 residents of Papua New Guinea, we prospectively assessed the effects...
متن کاملEcologic and biologic determinants of filarial antigenemia in bancroftian filariasis in Papua New Guinea.
The relationship between filarial antigenemia and lymphatic pathology was investigated in residents of 11 villages in an area of Papua New Guinea where Wuchereria bancrofti is endemic. Antigenemia was determined in 1322 persons by means of the Og4C3 antibody capture assay. Prevalence of antigenemia by village ranged from 61.7% to 98.2% and did not vary by sex. Antigen level increased with trans...
متن کاملReduction in Acute Filariasis Morbidity during a Mass Drug Administration Trial to Eliminate Lymphatic Filariasis in Papua New Guinea
BACKGROUND Acute painful swelling of the extremities and scrotum are debilitating clinical manifestations of Wuchereria bancrofti infection. The ongoing global program to eliminate filariasis using mass drug administration is expected to decrease this and other forms of filarial morbidity in the future by preventing establishment of new infections as a consequence of eliminating transmission by...
متن کاملDonovanosis in Papua New Guinea.
Clinical and epidemiological observations on 87 cases of donovanosis seen at Port Moresby General Hospital are presented, with detailed reports of three cases in which the disease was more severe. The circumstances of infection described were consistent with venereal transmission. Chloramphenicol and gentamicin were effective in curing the disease, while streptomycin was found to be ineffective...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2013
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmoa1207594